Laser
Acupuncture in Children with Headache
Gottschling S, et al. University Children’s Hospital,
Department of Pediatric Hematology and Oncology, Saarland University,
Kirrbergerstr., 66421 Homburg, Germany.
To investigate whether laser acupuncture is efficacious in children with
headache and if active laser treatment is superior to placebo laser treatment in
a prospective, randomized, double-blind, placebo-controlled trial of low level
laser acupuncture in 43 children (mean age (SD) 12.3 (+/-2.6) years) with
headache (either migraine (22 patients) or tension type headache (21 patients)).
Patients were randomized to receive a course of 4 treatments over 4 weeks with
either active or placebo laser. The treatment was highly individualised based on
criteria of Traditional Chinese medicine (TCM). The primary outcome measure was
a difference in numbers of headache days between baseline and the 4 months after
randomization. Secondary outcome measures included a change in headache severity
using a 10cm Visual Analogue Scale (VAS) for pain and a change in monthly hours
with headache. Measurements were taken during 4 weeks before randomization
(baseline), at weeks 1-4, 5-8, 9-12 and 13-16 from baseline. The mean number of
headaches per month decreased significantly by 6.4 days in the treated group
(p<0.001) and by 1.0 days in the placebo group (p=0.22). Secondary outcome
measures headache severity and monthly hours with headache decreased as well
significantly at all time points compared to baseline (p<0.001) and were as well
significantly lower than those of the placebo group at all time points
(p<0.001). We conclude that laser acupuncture can provide a significant benefit
for children with headache with active laser treatment being clearly more
effective than placebo laser treatment.
Pain. 2007 Nov 15
Source PubMed
[TOP]
Electro-Acupuncture of Tsusanli and Shangchuhsu Regulates Gastric Activity
Possibly Through Mediation of the Vagus-Solotary Complex
Wang JJ, et al. Department of Gastroenterology, Tangdu Hospital,
Fourth Military Medical University, Xi'an, China. Jingjie@fmmu.edu.cn
BACKGROUND/AIMS: Acupuncture has been reportedly used to treat gastrointestinal
diseases, however, its precise mechanism remains unknown. METHODOLOGY: In our
study, the effects and mechanism of electro-acupuncture (EA) at Tsusanli (ST
36), Shangchuhsu (ST 37) on regulation of gastric activity were observed.
RESULTS: EA at Tsusanli showed that gastric electric change was the most
obvious, with significantly higher frequency and wave amplitude compared with
that of the Shangchuhsu group and other groups. EA at Shangchuhsu demonstrated
that the change of gastric electric level was much higher than that of the non-acupoint
group and control group. After bilateral vagotomy, Tsusanlis was
electro-acupunctured, the changes of electro-gastric graph (EGG) weren't
significant with the control group. The frequency of electro-physiological
activity in nucleus of solitary tract (NTS) and dorsal motor nucleus of the
vagus nerve (DMV) in the Tsusanli group was markedly increased compared with
that in the other group. Fos and GFAP expression in NTS and DMV in the Tsusanli
group was significantly higher than that in other groups and control group. The
results have indicated that EA at Tsusanli and Shangchuhsu cannot only regulate
gastric activity, but also activate neurons and astrocytes in NTS and DMV. The
effects on regulation and activation of EA at Tsusanli were very obvious.
CONCLUSIONS: Our study suggests that this electroacupuncture regulation of
gastric activity may partially depend upon integrated nerve pathway and related
central neurons and astrocytes in the vagus-solitary complex.
Hepatogastroenterology. 2007 Sep;54(78):1862-7
Source: PubMed
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Fast Repair of
Oxidative DNA Damage by Phenylpropanoid Glycosides and Their Analogues
Shi Y, et al. School of Life Sciences.
The repair activities and reaction mechanisms of phenylpropanoid glycosides (PPGs)
and their analogues, isolated from Chinese folk medicinal herbs, towards
oxidative DNA damage were studied with pulse radiolytic technique. On pulse
irradiation of nitrogen-saturated 4 mM poly C aqueous solution containing one of
the tested polyphenols, 40 mM K(2)S(2)O(8) and 200 mM t-BuOH, the transient
absorption spectrum of the oxidative radical of poly C decays with the
concurrent formation of the phenoxyl radical of the tested polyphenols within
several tens of microseconds after the electron pulse irradiation. The result
indicated that there was a repair reaction between oxidative radical of poly C
and the tested polyphenols. The repair activities also were observed for the
tested polyphenols towards the radical cations of single-stranded DNA (ssDNA)
and double-stranded DNA (dsDNA). The rate constants were determined to be
3.7-6.4 x 10(9), 4.8-5.5 x 10(8) and 8.8-10.3 x 10(8) M(-1).sec(-1) for the
repair reactions of oxidative radical of poly C and radical cations of ssDNA and
dsDNA, respectively. The result of this study together with those of our
previous studies demonstrates that PPGs and their analogues can fast repair not
only the damage of deoxynucleoside and deoxynucleotide but also the damage of
integral DNA, with the latter being closer to a cellular condition.
Mutagenesis. 2007 Nov 13
Source: PubMed [TOP] |
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